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Custom medicine boxes for US over-the-counter, dietary-supplement, homeopathic, and personal-care brands. Folding cartons sized to your blister pack, bottle, tube, or sachet, printed on SBS with the Drug Facts or Supplement Facts panel laid out, tamper-evident seal options, and child-resistant construction available on request for regulated SKUs.
For US OTC, dietary-supplement, homeopathic, and personal-care brands packaging blister packs, bottles, tubes, and single-dose sachets.
Ensure safety & compliance with Custom Medicine Boxes featuring child-resistant closures, tamper-evident seals, and FDA-approved materials. Perfect for prescription drugs, supplements & OTC products.
About Custom Medicine Boxes
Packaging for a compliance-heavy category
OTC medicines and dietary supplements sit in the most heavily labeled aisle in retail. Every carton carries a required panel — Drug Facts for OTC, Supplement Facts for dietary supplements — plus dosing instructions, warnings, active-ingredient callouts, lot codes, expiration dates, and a scannable barcode. We print pharma- and supplement-grade folding cartons for US brands, start runs at 100 units with no setup, plate, or die charges, and include free 3D mockups, free physical samples on request, and free US shipping. Custom medicine boxes from this program are not a substitute for a validated pharma-CDMO packaging supply chain — customers remain responsible for full FDA compliance on the finished SKU.
Medicine and supplement carton formats
- Blister-pack cartons — folding cartons sized to hold one or more foil blister strips.
- Bottle cartons — reverse-tuck and auto-bottom cartons for tablet, capsule, and gummy bottles.
- Tube cartons — slim tuck-end cartons for topical ointments and creams.
- Sachet and stick-pack cartons — cartons sized for single-dose powder sachets and stick packs.
- Multi-pack and family cartons — larger cartons that group multiple SKUs into a value or family-pack presentation.
Drug Facts, Supplement Facts, and required panels
Every OTC and supplement SKU carries a required labeling panel — Drug Facts for OTC drugs regulated under FDA monograph rules, Supplement Facts for dietary supplements. We lay out the panel, active-ingredient callouts, dosing directions, warnings, storage, lot code, expiration date, NDC (where applicable), and a scannable barcode as part of free dieline support. Send us the exact panel copy and we will position it to the correct type-size and placement rules.
Tamper-evidence and child-resistant construction
For SKUs that need tamper evidence, we build in a tuck-and-seal closure, a tear-strip opening, or a shrink-band spec. Child-resistant folding-carton construction is available on request — tell us in the quote and we will pair the carton with a CR-tested locking fold.
Related regulated and health packaging
Medicine cartons often sit alongside supplement, CBD, and personal-care packaging. See CBD care boxes, cream boxes, and cosmetic boxes for adjacent regulated categories, or food and beverage packaging for supplement-adjacent formats.
Why US brands choose us for custom medicine boxes
Custom Box Printing manufactures custom medicine boxes from our US production facility, with free standard shipping anywhere in the contiguous United States and a 7–10 business day turnaround. We've printed custom medicine boxes for solo founders launching their first product line, growing direct-to-consumer brands placing 5,000-unit runs, and established retail brands with 50,000+ unit production schedules — and we treat all three the same: low MOQs (100-unit runs), free design support, no setup or die-plate charges, and a 3D digital mockup before anything goes to press.
Every custom medicine boxes order includes free in-house dieline and artwork support — our US-based designers will polish your existing files, or build a custom dieline from scratch to fit your exact product dimensions. We send you a 3D mockup to confirm look and proportions before production. For color-critical work, request a physical sample free — let’s talk about a customized sample so you can confirm the look before a full run.
Custom Medicine Boxes — specifications & options
| Box Style | Custom Medicine Boxes |
|---|---|
| Dimension ( L + W + H) | All Custom Sizes & Shapes |
| Quantities | Minimum 100 units |
| Paper Stock | 10pt to 28pt (60lb to 400lb) Eco-Friendly Kraft, E-flute Corrugated, Bux Board, Cardstock |
| Printing | No Printing, CMYK, CMYK + 1 PMS color, CMYK + 2 PMS colors |
| Finishing | Gloss Lamination, Matte Lamination, Gloss AQ, Gloss UV, Matte UV, Spot UV, Embossing, Foiling |
| Included Options | Die Cutting, Gluing, Scored, Perforation |
| Additional Options | |
| Proof | Flat View, 3D Mock-up, Physical Sampling (On request) |
| Turnaround | 4 – 8 Business Days, RUSH |
| Shipping | FLAT |
Materials, print, and finish options
Medicine and supplement cartons are a compliance-driven format. We print on 14pt to 22pt food- and pharma-grade SBS with low-migration inks, sized to your primary container. Matte and soft-touch lamination is common for consumer-facing OTC and supplement lines, while uncoated stock keeps a clinical or clean-label look. Tamper-evident tuck-and-seal closures, tear-strip openings, and child-resistant folds are available where the SKU requires them.
Available finishes include:
- Lamination: Gloss, matte, soft-touch, or velvet finish for a premium hand-feel.
- Foil stamping: Gold, silver, copper, or custom foil colors for high-visibility brand marks.
- Embossing & debossing: Tactile raised or recessed surface effects on logo or key artwork.
- Spot UV: Selective gloss coating that creates contrast against matte areas.
- Eco-friendly options: Recycled kraft, FSC-certified stocks, water-based inks, recyclable rigid constructions.
- Compliance: FDA food-safe inks; certified child-resistant constructions for CBD/cannabis where required.
If you're not sure which combination will work best for your custom medicine boxes, mention it in your quote request — our team will recommend the right material, print spec, and finish based on your product, budget, and brand positioning.
How to order your custom medicine boxes
- Request a quote — use the "Get Free Quote" button on this page, or call (855) 792-3890 (toll free). Tell us your box style, dimensions, quantity, material preferences, and any deadline.
- We respond within 1 business day with pricing, lead times, and material recommendations. No pressure, no commitment.
- Free design + 3D mockup — we build your dieline (or polish your existing artwork) and send you a 3D digital mockup to approve.
- Optional physical sample — request a custom sample (refunded on your first order) to hold the real box in hand — let’s talk it through.
- Production & free US shipping — once you approve, we print and ship in 7–10 business days, free anywhere in the United States.
Custom Medicine Boxes — Frequently Asked Questions
